NUI Galway

Faculty Member, Psychiatry

Lecturer & Research Scientist

College of Medicine, Nursing and Health Sciences

About

Latest Update:
Radio Interview: July 22, 2010
http://sciencespin.podomatic.com/


Co-Director, Clinical Neuroimaging Laboratory, NUI Galway
http://www.nuigalway.ie/psychiatry/research/neuroimaging_lab/

Irish Diffusion Imaging Group (IDIG)
http://www.idig.synthasite.com

Associate Editor, Translational Neuroscience
http://www.versita.com/science/medicine/tn/

Latest Findings Communicated:
-Most Recent: The Serotonin Transporter and Panic Disorder. Invited presentation at CINP (www.cinp2010.com) June 2010 Hong Kong. See weblink under websites on the left for more information.
-Upcoming: Genetic variation in cholinergic muscarinic-2 receptor gene modulates M(2) receptor binding in vivo and accounts for reduced binding in bipolar disorder. Invited presentation at the WFSBP (www.wfsbp-congress.org) May 2011 Prague.


Most Recent Awards:
-The Rafaelson Young Investigator Award, Collegium Internationale Neuropsychopharmacology (CINP) June 2010
-The Rising Star Award, European Psychiatric Association (EPA) Neuroimaging Section 2009


Prospective Students
Get in touch with me and see these resources for funding:
---For undergrads interested in summer experience check out the HRB Summer Student Scholarships. SFI UREKA has been discontinued.
---For prospective phd students - see IRCSET and the NIH graduate partnership program and the Wellcome Trust/NIH initiative, the NUI Galway Science Fellowships and the NUI Galway Medical School Fellowships.
---For postdoctoral funding see IRCSET


SELECT PUBLICATIONS
You can request a copy of any paper by e-mailing me
My ResearchID profile:
http://www.researcherid.com/rid/C-1323-2009

Genetic variation in cholinergic muscarinic-2 receptor gene modulates M(2) receptor binding in vivo and accounts for reduced binding in bipolar disorder. Cannon DM, Klaver JK, Gandhi SK, Solorio G, Peck SA, Erickson K, N Akula JS, Eckelman WC, Furey ML, Sahakian BJ, McMahon FJ, Drevets WC. Mol Psychiatry. 2010 Mar 30. [Epub ahead of print] PMID: 20351719

Genetic variation in HTR2A influences serotonin transporter binding potential as measured using PET and [11C]DASB. Laje G*, Cannon DM*, Allen AS, Klaver JM, Peck SA, Liu X, Manji HK, Drevets WC, McMahon FJ. Int J Neuropsychopharmacol. 2010 Jul;13(6):715-24. Epub 2010 Jan 5. PMID: 20047709 *These authors contributed equally to this work.

Amygdala volume in depressed patients with bipolar disorder assessed using high resolution 3T MRI: the impact of medication. Savitz J, Nugent AC, Bogers W, Liu A, Sills R, Luckenbaugh DA, Bain EE, Price JL, Zarate C, Manji HK, Cannon DM, Marrett S, Charney DS, Drevets WC. Neuroimage. 2010 Feb 15;49(4):2966-76. Epub 2009 Nov 17. PMID: 19931399

Reduced occipital and prefrontal brain volumes in dysbindin-associated schizophrenia.Donohoe G, Frodl T, Morris D, Spoletini I, Cannon DM, Cherubini A, Caltagirone C, Bossù P, McDonald C, Gill M, Corvin AP, Spalletta G. Neuropsychopharmacology. 2010 Jan;35(2):368-73. Epub .
PMID: 19794403

Dopamine Type-1 Receptor Binding in Major Depressive Disorder Assessed Using Positron Emission Tomography and [(11)C]NNC-112. Cannon DM, Klaver JM, Peck SA, Rallis-Voak D, Erickson K, Drevets WC. Neuropsychopharmacology. 2008 Oct 22. [Epub ahead of print] PMID: 18946469

Bcl-2 polymorphism influences gray matter volume in the ventral striatum in healthy humans. Salvadore G, Nugent AC, Chen G, Akula N, Yuan P, Cannon DM, Zarate CA Jr, McMahon FJ, Manji HK, Drevets WC. Biol Psychiatry. 2009 Oct 15;66(8):804-7. Epub 2009 Jul 9. Erratum in: Biol Psychiatry. 2009 Oct 15;66(8):808.
PMID: 19589501

Distinct profiles of neurocognitive function in unmedicated unipolar depression and bipolar II depression.Taylor Tavares JV, Clark L, Cannon DM, Erickson K, Drevets WC, Sahakian BJ. Biol Psychiatry. 2007 Oct 15;62(8):917-24. Epub 2007 Sep 7. PMID: 17825802

Elevated serotonin transporter binding in major depressive disorder assessed using positron emission tomography and [11C]DASB; comparison with bipolar disorder. Cannon DM, Ichise M, Rollis D, Klaver JM, Gandhi SK, Charney DS, Manji HK, Drevets WC. Biol Psychiatry. 2007 Oct 15;62(8):870-7. Epub 2007 Aug 2. PMID: 17678634

Serotonin transporter binding in bipolar disorder assessed using [11C]DASB and positron emission tomography. Cannon DM, Ichise M, Fromm SJ, Nugent AC, Rollis D, Gandhi SK, Klaver JM, Charney DS, Manji HK, Drevets WC. Biol Psychiatry. 2006 Aug 1;60(3):207-17. PMID: 16875929

Reduced muscarinic type 2 receptor binding in subjects with bipolar disorder. Cannon DM, Carson RE, Nugent AC, Eckelman WC, Kiesewetter DO, Williams J, Rollis D, Drevets M, Gandhi S, Solorio G, Drevets WC. Arch Gen Psychiatry. 2006 Jul;63(7):741-7. Erratum in: Arch Gen Psychiatry. 2006 Nov;63(11):1208. PMID: 16818863

Hot and cold cognition in unmedicated depressed subjects with bipolar disorder. Roiser JP, Cannon DM, Gandhi SK, Tavares JT, Erickson K, Wood S, Klaver JM, Clark L, Zarate CA Jr, Sahakian BJ, Drevets WC. Bipolar Disord. 2009 Mar;11(2):178-89.PMID: 19267700

A comparison of cognitive functioning in medicated and unmedicated subjects with bipolar depression. Holmes MK, Erickson K, Luckenbaugh DA, Drevets WC, Bain EE, Cannon DM, Snow J, Sahakian BJ, Manji HK, Zarate CA Jr.
Bipolar Disord. 2008 Nov;10(7):806-15. PMID: 19032712

Mood-congruent bias in affective go/no-go performance of unmedicated patients with major depressive disorder. Erickson K, Drevets WC, Clark L, Cannon DM, Bain EE, Zarate CA Jr, Charney DS, Sahakian BJ. Am J Psychiatry. 2005 Nov;162(11):2171-3. PMID: 16263859

Cortical abnormalities in bipolar disorder investigated with MRI and voxel-based morphometry. Nugent AC, Milham MP, Bain EE, Mah L, Cannon DM, Marrett S, Zarate CA, Pine DS, Price JL, Drevets WC. Neuroimage. 2006 Apr 1;30(2):485-97. Epub 2005 Oct 26. PMID: 16256376

In vitro neuronal and vascular responses to 5-HT in rats chronically exposed to MDMA. Cannon DM, Keenan AK, Guiry PJ, Buon C, Baird AW, McBean GJ. Br J Pharmacol. 2001 Dec;134(7):1455-60. PMID: 11724751

In vitro neuronal and vascular responses to 5-hydroxytryptamine: modulation by 4-methylthioamphetamine, 4-methylthiomethamphetamine and 3,4-methylenedioxymethamphetamine. Murphy J, Flynn JJ, Cannon DM, Guiry PJ, McCormack P, Baird AW, McBean GJ, Keenan AK. Eur J Pharmacol. 2002 May 24;444(1-2):61-7. PMID: 12191583